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肖立華

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肖立華,男,漢族,1962年3月生,湖南華容縣人,博士研究生學歷,獸醫專業學位博士學位。1993至2017年在美國疾病預防控制中心工作,先後任副研究員和研究員。2018年全職回國工作。現任華南農業大學特聘教授博士生導師[1]

基本信息

人物說明----華南農業大學特聘教授、博士生導師

出生日期----1962年3月

出生地點----湖南華容縣

國 籍 ---- 中國

職 業 ---- 教育科研工作者

畢業院校----湖南農業大學中國農業大學、美國緬因大學

人物經歷

教育背景

1978-1982:學士,湖南農業大學,獸醫學專業

1982-1985:碩士,中國農業大學,獸醫寄生蟲學專業

1987-1990:博士,美國緬因大學,寄生蟲學專業

工作經歷

1985-1987:講師,東北農業大學

1991-1992:博士後,美國俄亥俄州立大學

1993-2017:副研究員/研究員,美國疾病預防控制中心

2018至今:特聘教授,華南農業大學

研究方向

以食源性和水源性病原體(如隱孢子蟲、賈第蟲、環孢子蟲和微孢子蟲等)為研究對象,長期從事其病原生物學、分子檢測和溯源及生態學研究。

主要研究方向包括:

1. 食源性、水源性新發病原的生物學、遺傳學、分子流行病學和生態學

2. 食源性、水源性新發病原的侵入、跨種傳播及致病機理

3. 食源性、水源性新發病原的比較和功能基因組學及其應用

主要成就

專著教材

1.Xiao L., Ryan U., and Feng Y. (eds) Biology of Foodborne Parasites. CRC Press, Boca Raton, FL, 2015, 507 pages.

2.Ryan U., Power M., and Xiao L. (eds) Cryptosporidium and Other Waterborne Protozoa. Experimental Parasitology, 2010, Volume 124, Issue 1 (Special Issue), 146 pages.

3.Fayer R. and Xiao L. (eds) Cryptosporidium and Cryptosporidiosis, 2nd edition, CRC Press and IWA Publishing, Boca Raton, FL, 2008, 560 pages.

4.Xiao L., Alderisio K., and Singh A. Development and Standardization of a Cryptosporidium Genotyping Tool for Water Samples. Awwa Research Foundation, Denver, Colorado, 2006, 116 pages. 1P-3.5C-91101-03/06-CM.

發表論文

1.Yaoyu Feng, Una.Ryan, Lihua Xiao*. Genetic diversity and population structure of Cryptosporidium. Trends in Parasitology, 2018, 34: 997-1011.

2.Yuanfei Wang, Na Li, Yaqiong Guo, Lin Wang, Rui Wang, Yaoyu Feng*, Lihua Xiao*. Persistent Occurrence of Cryptosporidium hominis and Giardia duodenalis Subtypes in a Welfare Institute, Frontiers in Microbiology, 2018, 9: 2830.

3.Li N., Neumann N.F., Ruecker N., Alderisio K.A., Sturbaum G.D., Villegas E.N., Chalmers R., Monis P., Feng Y., and Xiao L.*. Development and evaluation of three real-time PCR assays for genotyping and source tracking Cryptosporidium in water. Applied and Environmental Microbiology, 2015, 81: 5845-5854.

4.Tang K., Guo Y., Zhang L., Rowe L.A., Roellig D.M., Frace M.A., Li N., Liu S., Feng Y.*, and Xiao L.*. Genetic similarities between Cyclospora cayetanensis and cecum-infecting avian Eimeria spp. in apicoplast and mitochondrial genomes. Parasites & Vectors, 2015, 8: 358.

5.Guo Y., Li N., Lysen C., Frace M., Tang K., Sammons S., Roellig D.M., Feng Y.*, and Xiao L.* Isolation and enrichment of Cryptosporidium DNA and verification of DNA purity for whole-genome sequencing. Journal of Clinical Microbiology, 2015, 53: 641-647.

6.Guo Y., Cebelinski E., Matusevich C., Alderisio K.A., Lebbad M., McEvoy J., Roellig D.M., Yang C., Feng Y.*, and Xiao L.* Subtyping novel zoonotic pathogen Cryptosporidium chipmunk genotype I. Journal of Clinical Microbiology, 2015, 53: 1648-1654.

7.Feng Y.*, Tiao N., Hlavsa M., Li N., and Xiao L.* Multilocus sequence typing of an emerging Cryptosporidium hominis subtype in the United States. Journal of Clinical Microbiology, 2014, 52:524-530.

8.Karim M.R., Wang R., Dong H., Zhang L.*, Li J., Zhang S., Rume F.I., Qi M., Jian F., Sun M., Yang G., Zou F., Ning C., Xiao L.*. Genetic polymorphism and zoonotic potential of Enterocytozoon bieneusi from nonhuman primates in China. Applied and Environmental Microbiology, 2014, 80, 1893-1898.

9.Wang Y., Yang W., Cama V., Wang L., Cabrera L., Ortega Y., Bern C., Feng Y.*, Gilman R., and Xiao L.* Population genetics of Cryptosporidium meleagridis in humans and birds: evidence for cross-species transmission. International Journal for Parasitology, 2014, 44: 515-521.

10.Karim M.R., Dong H., Yu F., Jian F., Zhang L.*, Wang R., Zhang S., Rume F.I., Ning C., and Xiao L.* Genetic diversity in Enterocytozoon bieneusi from dogs and cats in China: host specificity and public health implications. Journal of Clinical Microbiology, 2014, 52: 3297-3302.

11.Hu Y., Feng Y.*, Huang C., and Xiao L.* Occurrence, source, and human infection potential of Cryptosporidium and Enterocytozoon bieneusi in drinking source water in Shanghai, China, during a pig carcass disposal incident. Environmental Science & Technology, 2014, 48: 14219-14227.

12.Li W., Cama V., Feng Y., Gilman R.H., Bern C., Zhang X.*, and Xiao L.* Population genetic analysis of Enterocytozoon bieneusi in humans. International Journal for Parasitology, 2012, 42: 287-293

13.Li N., Xiao L.*, Wang L., Zhao S., Zhao X., Duan L., Guo M., Liu L., and Feng Y.* Molecular surveillance of Cryptosporidium spp., Giardia duodenalis, and Enterocytozoon bieneusi by genotyping and subtyping parasites in wastewater. PLoS Neglected Tropical Diseases, 2012, 6: e1809.

14.Ye J., Xiao L., Ma J., Guo M., Liu L. and Feng Y. Anthroponotic enteric parasites in monkeys in public park, china. Emerging Infectious Diseases, 2012, 18: 1640-1643

15.Feng Y.* and Xiao L.* The zoonotic potential and molecular epidemiology of Giardia and giardiasis. Clinical Microbiology Reviews, 2011, 24: 110-140

16.Feng Y., Yang W., Ryan U., Zhang L., Kvac M., Koudela B., Modry D., Li N.,Fayer R., and Xiao L.* Development of a multilocus sequence typing tool for Cryptosporidium muris and Cryptosporidium andersoni. Journal of Clinical Microbiology, 2011, 49: 34-41

17.Wang R., Wang, H., Sun Y., Zhang L.*, Jian F., Qi M., Ning C., and Xiao L.* Characteristics of Cryptosporidium transmission in pre-weaned dairy cattle in Henan, China. Journal of Clinical Microbiology, 2011, 49: 1077-1082

18.Feng Y.*, Zhao X., Chen J., Jin W., Zhou X., Li N., Wang L., and Xiao L.* Occurrence, source, and human infection potential of Cryptosporidium and Giardia spp. in source and tap water in Shanghai, China. Applied and Environmental Microbiology, 2011, 77: 3609-3616

19.Feng Y.*, Li N., Dearen T., Lobo M. L., Matos O., Cama V., and Xiao L.* Development of a multilocus sequence typing tool for high resolution genotyping of Enterocytozoon bieneusi. Applied and Environmental Microbiology, 2011, 77: 4822-4828

20.Zhou Y., Lv B., Wang Q., Wang R., Jian F., Zhang L.*, Ning C., Fu K., Wang Y., Qi M., Yao H., Zhao J., Zhang X., Sun Y., Shi K., Arrowood M.A., and Xiao L.* Prevalence and molecular characterizationof Cyclospora cayetanensis, Henan, China. Emerging Infectious Diseases, 2011, 17: 1887-1890

21.Li W., Kiulia N.M., Mwenda J.M., Nyachieo A., Taylor M.B., Zhang X., and Xiao L.* Cyclospora papionis, Cryptosporidium hominis, and human-pathogenic Enterocytozoon bieneusi in captive baboons in Kenya. Journal of Clinical Microbiology, 2011, 49: 4326-4329

22.Shi K., Jian F., Lv C., Ning C., Zhang L.*, Ren X., Dearen T.K., Li N., Qi M., and Xiao L.* Prevalence, genetic characteristics, and zoonotic potential of Cryptosporidium in farm rabbits in China. Journal of Clinical Microbiology, 2010, 48: 3263-3266

獲獎記錄

2018:Highly Cited Researchers, Web of Science

2018:Excellence in Laboratory Research, National Center for Emergening and Zoonotic Infectious Diseases, CDC, Atlanta, USA

2004:Unit Citation Award, National Oceanic Atmospheric Administration

2008:CDC Public Health Epidemiology and Laboratory Research Award, Atlanta, USA

2008:NCZVED/CDC Laboratory Science Mentorship Award, Atlanta, USA

2010:Top Cited Article 2008-2010, International Journal for Parasitology, Elsevier

2011:Outstanding Service, American Society for Microbiology Minority Mentoring Program, USA.

2012:Top Cited Article 2009-2011, Experimental Parasitology, Elsevier

2012:美國寄生蟲學會傑出成就獎「Henry Baldwin Ward Medal」

2020年11月,獲得第八屆中國僑界貢獻獎二等獎[2]

社會任職

2018-至今:Frontiers in Microbiology副主編

2017-至今: Parasitology Research副主編

2014-2020:Clinical Microbiology Reviews副主編

2019-至今:One Health編委

2018-至今:Veterinary Parasitology編委

2017-至今:Food and Waterborne Parasitology編委

2010-至今:Clinical Microbiology Reviews編委

2014-2019:Journal of Clinical Microbiology編委

2010-2019:Applied and Environmental Microbiology編委

2012-至今:Experimental Parasitology編委

2007-至今:The Open Journal of Parasitology編委

2009: Experimental Parasitology,Special issue特邀編輯

2009-至今:CryptoDB、MicrobeNet、NIH-CDC-HIVMA/IDSA、USEPA SAMPathogen Methods諮詢委員會委員

近年來,參與以下機構的項目評審:U.S. Environmental Protection Agency (EPA), USDA Small Business Grants, Israel Science Foundation (ISF), National Research Foundation (Singapore), the United States-Israel Binational Agricultural Research & Development Fund (BARD), Wellcome Trust, National Sciences and Engineering Research Council of Canada (NSERC), 中國自然科學基金委, Grant Agency of the Czech Republic (GACR), Austrian Science Fund (FWF), Children’s Research Centre (Republic of Ireland), and Qatar Foundation (Qatar).

參考來源