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李伟明，男，(1961年9月- )出生于 国家"千人计划"特聘教授。
简介
| 李伟明 | |
|---|---|
| 出生 | 1961年9月1日 |
| 职业 | 上海海洋大学教授 |
1982年毕业于上海水产大学淡水渔业专业(本科)，1987年毕业于上海水产大学鱼类生理学专业，获农学硕士学位，1994年毕业于美国明尼苏达大学渔业和神经科学专业特，获理学博士学位。现任美国密歇根州立大学终身教授、终身讲席教授(Chair Professor)。
研究领域编辑
化学生理、信息素通信、鱼类信息素调控，鱼类生殖及应激内分泌调控，无颌鱼类进化，基因组注释及功能基因组学，入侵种生物控制。先后主持美国NIH、NSF、美国能源部、SEA GRANT、五大湖渔业委员会、五大湖渔业信托基金、五大湖保护基金和加拿大科学与工程研究部 (NSERC)的基金资助，总经费超过1100万美元。近年来，在《SCIENCE》、《PNAS》、《JOURNAL OF NEUROSCIENCE》、《BMC Evolutionary Biology》等国际顶级学术期刊发表多篇具有很强学术影响力的论文。
海七鳃鳗信息素通信学术报告
2018年11月21日，李伟明应邀中国水产研究所，所开展学术交流并作报告。与中国水产研究所相关科研人员和研究生20馀人参加了学术交流会。会议由科研处副处长么宗利主持。
报告会上，李伟明教授作了题为“海七鳃鳗信息素通信”的学术报告，介绍了从寻找雄性海七鳃鳗如何释放性信息素这一生物学现象入手，利用化学手段解析性信息素的化学结构，再到合成该性信息素释放到河流中进行雌性海七鳃鳗的诱捕实验，以及其研究团队利用大规模筛选的方式，在细胞水平和分子水平确定性信息素及其受体相互作用的分子机理方面研究的最新研究进展。会后，与相关科研人员围绕海水鱼基因组解析、水生动物盐碱适应性机制等具体问题进行沟通与交流。 [1]
学术影响力的高水平论文
在《Science》、《Nature Genetics》、《PNAS》、《Journal OF Neuroscience》、《Natural Product Reports》、《Organic Letters》等国际顶级学术期刊发表多篇具有很强学术影响力的高水平论文。[2]
发表论文编辑
(1) Close DA, Yun S-S, McCormick, SD, Wildbill AJ andLi W. 2010. 11-Deoxycortisol is a corticosteroid hormone in the lamprey Proceedings of the National Academy of Sciences of the United States of America 107: 13942~13947.
(2) Libants S, Carr K, Wu H, Teeter JH, Chung-Davidson Y-W, Zhang Z, Wilkerson C &Li W(2009). The sea lamprey Petromyzon marinus genome reveals the early origin of several chemosensory receptor families in the vertebrate lineage. BMC Evolutionary Biology. 9: 180-194.
(3) Johnson NS, Yun S-S, Thompson H, Brant C,Li W(2009) A synthesized pheromone induces upstream movement in female sea lamprey and summons them into traps. Proceedings of the National Academy of Sciences of the United States of America 106: 1021-1026.
(4)Chung-Davidson Y-W, Rees CB, Bryan MB,Li W(2008) Neurogenic and Neuroendocrine Effects of Goldfish Pheromones. Journal of Neuroscience 28(53): 14492-14499.
(5)Chung-Davidson Y-W, Bryan MB, Teeter J, Bedore CN,Li W(2008) Neuroendocrine and behavioral responses to weak electric fields in adult sea lampreys (Petromyzon marinus). Hormones and Behavior 54(1): 34-40.
(6)Bryan MB, Scott AP,Li W(2008) Sex steroids and their receptors in lampreys. Steroids. 73(1) 1-12.
(7)Yun S-S,Li W(2007) Identification of an antimicrobial aminosterol squalamine in the white blood cells of sea lamprey, Petromyzon marinus. Journal of Lipid Research 48: 2579-2586
(8)Bryan MB, Scott AP,Li W(2007) The sea lamprey (Petromyzon marinus) has a receptor for androstendione. Biology of Reproduction. 77: 688-696.(This article was highlighted in the Editors’ Choice section, Science 317: 723.)
(9)Li W, Twohey M, Jones M, Wagner M (2007) Research to guide use of pheromones to control sea lamprey. Journal of Great Lakes Research. 33 (special issue 2): 70-86.
(10)Young BA, Bryan MB, Glenn JR, Yun S-S, Scott AP,Li W(2007) Dose-response relationship of 15 alpha-hydroxylated sex steroids to gonadotropin-releasing hormones and pituitary extract in male sea lampreys (Petromyzon marinus). General and Comparative Endocrinology 151(1): 108-115.
(11)Belanger RM, Corkum LD,Li W,Zielinski BS (2006) Olfactory sensory input increases gill ventilation in male round gobies (Neogobius melanostomus) during exposure to steroids. Comparative Biochemistry and Physiology a-Molecular & Integrative Physiology 144(2): 196-202.
(12)Bryan MB, Young BA, Close DA, Semeyn J, Robinson TC, Bayer J,Li W(2006) Comparison of synthesis of 15 alpha-hydroxylated steroids in males of four North American lamprey species. General and Comparative Endocrinology 146(2): 149-156.
(13)Corkum LD, Arbuckle WJ, Belanger AJ, Gammon DB,Li W, Scott AP, Zielinski B (2006) Evidence of a male sex pheromone in the round goby (Neogobius melanostomus). Biological Invasions 8(1): 105-112.
(14)Johnson NS , Luehring MA, Siefkes MJ,Li W(2006) Mating pheromone reception and induced behavior in ovulating female sea lampreys. North American Journal of Fisheries Management 26(1): 88-96.
(15) Arbuckle WJ, Belanger AJ, Corkum LD, Zielinski BS,Li W, Yun SS, Bachynski S, Scott AP (2005) In vitro biosynthesis of novel 5 beta-reduced steroids by the testis of the round goby, Neogobius melanostomus. General and Comparative Endocrinology 140(1): 1-13.
(16) Bryan MB, Zalinski D, Filcek KB, Libants S,Li W, Scribner KT (2005) Patterns of invasion and colonization of the sea lamprey (Petromyzon marinus) in North America as revealed by microsatellite genotypes. Molecular Ecology 14(12): 3757-3773.
(17) Gammon DB,Li W, Scott AP, Zielinski BS, Corkum LD (2005) Behavioural responses of female Neogobius melanostomus to odours of conspecifics. Journal of Fish Biology 67(3): 615-626.
(18) Johnson NS , Siefkes MJ,Li W(2005) Capture of ovulating female sea lampreys in traps baited with spermiating male sea lampreys. North American Journal of Fisheries Management 25(1): 67-72.
(19)Li W(2005). Potential multiple functions of a male sea lamprey pheromone. Chemical Senses 30: I307-I308.
(20) Rees CB, McCormick SD,Li W(2005) A non-lethal method to estimate CYP1A expression in laboratory and wild Atlantic salmon (Salmo salar). Comparative Biochemistry and Physiology C-Toxicology & Pharmacology 141(3): 217-224.
(21) Rees CB, Wu H,Li W(2005) Cloning of CYP1A in Atlantic salmon (Salmo salar). Aquaculture 246(1-4): 11-23.
(22)Siefkes MJ, Winterstein SR,Li W(2005) Evidence that 3-keto petromyzonol sulphate specifically attracts ovulating female sea lamprey, Petromyzon marinus. Animal Behaviour 70: 1037-1045.
(23) BeLanger AJ, Arbuckle WJ, Corkum LD, Gammon DB,Li W, Scott AP, Zielinski BS (2004) Behavioural and electrophysiological responses by reproductive female Neogobius melanostomus to odours released by conspecific males. Journal of Fish Biology 65(4): 933-946.
(24) Bryan MB, Scott AP, Cerny I, Young BA,Li W(2004) 15 alpha-Hydroxyprogesterone in male sea lampreys, Petromyzon marinus L. Steroids 69(7): 473-481.
(25) Butterworth KG,Li W, McKinley RS (2004) Carbon and nitrogen stable isotopes: a tool to differentiate between Lepeophtheirus salmonis and different salmonid host species? Aquaculture 241(1-4): 529-538.
(26) Chung-Davidson Y-W, Rees CB, Wu H, Yun SS,Li W(2004) β-naphthoflavone induction of CYP1A in brain of juvenile lake trout (Salvelinus namaycush Walbaum). Journal of Experimental Biology. 207: 1533-1542.
(27) Chung-Davidson Y-W, Yun SS, Teeter J,Li W(2004) Brain pathways and behavioral responses to weak electric fields in parasitic sea lampreys (Petromyzon marinus). Behavioral Neuroscience. 118(3): 611-619.
(28)Li W, Chung-Davidson Y-W, Siefkes MJ, Wu H, Rees CB (2004) Pheromone regulation of reproductive neuroendocrine in the sea lamprey. Integrative and Comparative Biology 44(6): 592-592.
(29) Rees CB,Li W(2004) Development and application of a real-time quantitative PCR assay for determining CYP1A transcripts in three genera of salmonids. Aquatic Toxicology 66(4): 357-368.
(30) Siefkes MJ,Li W(2004) Electrophysiological evidence for detection and discrimination of pheromonal bile acids by the olfactory epithelium of female sea lampreys (Petromyzon marinus). Journal of Comparative Physiology a-Neuroethology Sensory Neural and Behavioral Physiology 190(3): 193-199.
(31) Young BA, Bryan MB, Sower SA,Li W(2004) The effect of chemosterilization on sex steroid production in male sea lampreys. Transactions of the American Fisheries Society 133(5): 1270-1276.
(32) Young BA, Bryan MB, Sower SA, Scott AP,Li W(2004) 15 alpha-hydroxytestosterone induction by GnRH I and GnRH III in Atlantic and Great Lakes sea lamprey (Petromyzon marinus L.). General and Comparative Endocrinology 136(2): 276-281.
(33) Bryan MB, Libants SV, Warrillow JA,Li W, Scribner KT (2003) Polymorphic microsatellite markers for the landlocked sea lamprey, Petromyzon marinus. Conservation Genetics 4(1): 113-116.
(34) Bryan MB, Scott AP, Cerny I, Yun SS,Li W(2003) 15 alpha-hydroxytestosterone produced in vitro and in vivo in the sea lamprey, Petromyzon marinus. General and Comparative Endocrinology 132(3): 418-426.
(35) Frontini A, Zaidi AU, Hua H, Wolak TP, Greer CA, Kafitz KW,Li W, Zielinski BS (2003) Glomerular territories in the olfactory bulb from the larval stage of the sea lamprey Petromyzon marinus. Journal of Comparative Neurology 465(1): 27-37.
(36)Li W, Siefkes MJ, Scott AP, Teeter JH (2003) Sex pheromone communication in the sea lamprey: Implications for integrated management. Journal of Great Lakes Research 29: 85-94.
(37)Li W, Scott AP, Siefkes MJ, Yun SS, Zielinski BS (2003) A male pheromone in the sea lamprey (Petromyzon marinus): an overview. Fish Physiology and Biochemistry 28(1-4): 259-262.
(38) Rees CB, McCormick SD, Vanden Heuvel JP,Li W(2003) Quantitative PCR analysis of CYP1A induction in Atlantic salmon (Salmo salar). Aquatic Toxicology 62(1): 67-78.
(39) Siefkes MJ, Bergstedt RA, Twohey MB,Li W(2003) Chemosterilization of male sea lampreys (Petromyzon marinus) does not affect sex pheromone release. Canadian Journal of Fisheries and Aquatic Sciences 60(1): 23-31.
(40) Siefkes MJ, Scott AP, Zielinski BS, Yun SS,Li W(2003) Male sea lampreys, Petromyzon marinus L., excrete a sex pheromone from gill epithelia. Biology of Reproduction 69(1): 125-132.
(41) Twohey MB, Sorensen PW,Li W(2003) Possible applications of pheromones in an integrated sea lamprey management program. Journal of Great Lakes Research 29: 794-800.
(42) Yun SS, Scott AP, Bayer JM, Seelye JG, Close DA,Li W(2003) HPLC and ELISA analyses of larval bile acids from Pacific and western brook lampreys. Steroids 68(6): 515-523.
(43) Yun SS, Scott AP,Li W(2003) Pheromones of the male sea lamprey, Petromyzon marinus L.: structural studies on a new compound, 3-keto allocholic acid, and 3-keto petromyzonol sulfate. Steroids 68(3): 297-304.
(44) Zielinski BS, Arbuckle W, Belanger A, Corkum LD,Li W, Scott AP (2003) Evidence for the release of sex pheromones by male round gobies (Neogobius melanstomus). Fish Physiology and Biochemistry 28(1-4): 237-239.
(45)Li W, Scott AP, Siefkes MJ, Yan HG, Liu Q, Yun SS, Gage DA (2002) Bile acid secreted by mate sea lamprey that acts as a sex pheromone. Science 296(5565): 138-141.
(46) Yun S-S, Siefkes MJ, Scott AP,Li W(2002) Development and application of an ELISA for a sex pheromone released by the male sea lamprey (Petromyzon marinus L.). General and Comparative Endocrinology, 129: 163-170