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賈焱檢視原始碼討論檢視歷史

事實揭露 揭密真相
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賈焱
北京工商大學

賈焱,男,北京工商大學教授。

研究方向

主要從事精準護膚與皮膚健康體系研究,以皮膚問題為導向,基於生命科學、皮膚科學、藥劑學等新興技術,開發針對不同皮膚類型人群的化妝品。

社會兼職

北京市黨外高級知識分子聯誼會 理事

美中化妝品專業委員會(CACPA) 會員

北京中西醫結合學會環境與健康專業委員會 委員

Frontiers in Sustainable Food Systems雜誌 編委

Journal of Dermatological Science、Journal of Cosmetic Dermatology等學術期刊審稿人

科研項目

[1] 主持國家自然科學基金,項目名稱:納豆激酶分子內分子伴侶與成熟肽斷裂的分子機理研究,項目號:31501415.

[2] 主持北京市屬高校青年拔尖人才項目,項目號:CIT&TCD201804027.

[3] 主持北京市教委科研計劃面上項目,項目名稱:中國男性雄激素性脫髮的病因研究與頭皮脂質成分分析,項目號:SQKM201610011008.

[4] 主持北京工商大學學位與研究生教育改革項目,項目名稱:適用於我校化妝品科學與技術專業的輪轉導師制研究.

[5] 主持企事業單位委託課題,項目名稱:XX系列化妝品的開發.

[6] 主持企事業單位委託課題,項目名稱:XX化妝品對皮膚脂質組的影響及機制研究

[7] 主持企事業單位委託課題,項目名稱:基於質譜技術的皮膚脂質成分分析.

[8] 主持企事業單位委託課題,項目名稱:皮膚角質管理策略研究.

[9] 主持企事業單位委託課題,項目名稱:XX面膜中熒光劑的含量分析.

[10] 主持企事業單位委託課題,項目名稱:化妝品生產配方、工藝、標準情況調研

學術成果

論文

[1] Mingyue Zhou, Hecong Wang, Manli Yang, Ming Yang, Ying Gao, Yan Jia*. Lipidomic analysis of facial skin surface lipids reveals an altered lipid profile in infant acne. British Journal of Dermatology, 2020, 182(3): 817-818.

[2] Mingyue Zhou#, Yao Gan#, Congfen He, Zhou Chen, Yan Jia*. Lipidomics reveals skin surface lipid abnormity in male youth acne. British Journal of Dermatology. 2018. 179(3):732-740.

[3] Manli Yang, Jingyu Wu, Qingrong Huang, Yan Jia*. Probing the role of catalytic triad on the cleavage between intramolecular chaperone and NK mature peptide. Journal of Agricultural and Food Chemistry. 2021, 69(7): 2348-2353.

[4] Manli Yang, Mingyue Zhou, Yuan Li, Hong Huang, Yan Jia*. Lipidomic analysis of facial skin surface lipid reveals the causes of pregnancy-related skin barrier weakness. Scientific Reports. 2021, 2(11): 3229.

[5] Yan Jia*, Yao Gan, Congfen He, Zhou Chen, Cheng Zhou. The mechanism of skin lipids influencing skin status. Journal of Dermatological Science. 2018, 89(2):112-119.

[6] Yan Jia*, Mingyue Zhou, Hong Huang, Yao Gan, Manli Yang, Ruiheng Ding. Characterization of circadian human facial surface lipid composition. Experimental Dermatology. 2019, 28(7): 858-862.

[7] Mingyue Zhou, Manli Yang, Yumei Zheng, Kun Dong, Liya Song, Congfen He, Wei Liu, Yiyu Wang, Yan Jia*. Skin surface lipidomics revealed the correlation between lipidomic profile and grade in adolescent acne. Journal of Cosmetic Dermatology, 2020, 19(12): 3349-3356.

[8] Mingyue Zhou, Yao Gan, Manli Yang, Congfen He, Yan Jia*. Lipidomics analysis of facial skin surface lipids between forehead and cheek: Association between lipidome, TEWL, and pH. Journal of Cosmetic Dermatology, 2020, 19(10): 2752-2758.

[9] Le Cui, Congfen He, Linna Fan, Yan Jia*. Application of lipidomics to reveal differences in facial skin surface lipids between males and females. Journal of Cosmetic Dermatology. 2018. doi: 10.1111/jocd.12474.

[10] Xinchao Li, Congfen He, Zhou Chen, Cheng Zhou, Yao Gan, Yan Jia*. A review of the role of sebum in the mechanism of acne pathogenesis. Journal of Cosmetic Dermatology. 2017, 16(2):168-173.

[11] Xinchao Li, Congfen He, Liya Song, Ting Li, Shumei Cui, Liping Zhang, Yan Jia*. Antimicrobial activity and mechanism of Larch bark procyanidins against Staphylococcus aureus. Acta Biochimica et Biophysica Sinica. 2017, 49(12):1058-1066.

[12] Manli Yang, Mingyue Zhou, Hecong Wang, Ming Yang, Ying Gao, Yan Jia*. Lipidomics reveals the role of glycoceramide and phosphatidylethanolamine in infantile acne. Journal of Cosmetic Dermatology. 2021, 20(3): 947-954.

[13] Linna Fan, Congfen He, Ligang Jiang, Yongxian Bi, Yinmao Dong, Yan Jia*. Brief analysis of causes of sensitive skin and advances in evaluation of anti-allergic activity of cosmetic products. International Journal of Cosmetic Science. 2016, 38(2):120-127.

[14] Yan Jia*, Yingjie Sun, Congfen He, Shuangyan Tang, Enguang Zhu. Research progress on the mechanism of intramolecular chaperone. Progress in Biochemistry & Biophysics. 2016, 43(5):443-448.

[15] Yan Jia, Xinhua Cao, Yu Deng, Wei Bao, Changyan Tang, Hanjing Ding, Zhongliang Zheng, Guolin Zou. Four residues of propeptide are essential for precursor folding of nattokinase. Acta Biochimica et Biophysica Sinica. 2014, 46(11):957-964.

[16] Yan Jia, Hui Liu, Wei Bao, Meizhi Weng, Wei Chen, Yongjun Cai, Zhongliang Zheng, Guolin Zou. Functional analysis of propeptide as an intramolecular chaperonefor in vivo folding of subtilisin nattokinase. FEBS Letters. 2010, 584(23):4789-4796.

[17] Linna Fan, Yan Jia, Le Cui, Xinchao Li, Congfen He*. Analysis of sensitive skin barrier function: basic indicators and sebum composition. International Journal of Cosmetic Science. 2018, 40(2):117-126.

[18] Chaoning Liang, Yi Zhang, Yan Jia, Wenzhao Wang, Youhai Li, Shikun Lu, Jianming Jin*, Shuangyan Tang*. Engineering a Carbohydrate-processing Transglycosidase into Glycosyltransferase for Natural Product Glycodiversification. Scientific Reports. 2016, 6:21051.

[19] Le Cui, Yan Jia, Zhiwei Cheng, Ying Gao, Gaolei Zhang, Jingyi Li, Congfen He*. Advancements in the maintenance of skin barrier/skin lipid composition and the involvement of metabolic enzymes. Journal of Cosmetic Dermatology. 2016, 15(4):549-558.

[20] Hua Cheng, Yan Jia, Ling Wang, Xiaoying Liu, Guangrong Liu, Li Li, Congfen He*. Isolation and structural elucidation of a novel homogenouspolysaccharide from Tricholoma matsutake. Natural Product Research. 2016, 30(1):58-64.

[21] Meizhi Weng, Xiongwei Deng, Wei Bao, Li Zhu, Jieyuan Wu, Yongjun Cai, Yan Jia, Zhongliang Zheng, Guolin Zou*. Improving the Activity of the Subtilisin Nattokinase by Site-directed Mutagenesis and Molecular Dynamics Simulation. Biochemical and Biophysical Research Communications. 2015, 465:580-586.

[22] Hanjing Ding, Hui Liu, Yan Yin, Ying Ding, Yan Jia, Qingming Chen, Guolin Zou*. Zhongliang Zheng. Insights into the modulation of optimum pH by a single histidine residue in arginine deiminase from Pseudomonas aeruginosa. Biological Chemistry. 2012, 393(9):1013-1024.

[23] Yongjun Cai, Wei Bao, Shujun Jiang, Yan Jia, Zhongliang Zheng, Guolin Zou*. Directed evolution improves the fibrinolytic activity of nattokinase from Bacillus natto. FEMS microbiology letters. 2011, 325(2):155-161.

[24] 甘瑤, 何聰芬, 賀可可, 李欣超, 賈焱*. 基於脂質組學的青年女性早晚面部皮膚表面脂質差異分析. 日用化學工業. 2018, 48(3):151-161.

[25] 崔樂, 賈焱, 成志偉, 高瑩, 張高磊, 李靖怡, 何聰芬*. 維持皮膚屏障研究進展--脂質的分泌及組成. 中國皮膚性病學雜誌. 2016, (6):640-643.

[26] 崔樂, 高瑩, 張高磊, 賈焱, 李靖怡, 成志偉, 何聰芬*. 皮膚屏障結構脂質研究進展-脂質代謝相關酶. 中國皮膚性病學雜誌. 2016, (9):964-967.

[27] 王琪, 劉向慧, 賈小凡, 宋麗雅, 賈焱, 何聰芬*. 皮膚脂質成分分析方法研究進展. 日用化學工業. 2014, 44(4):226-230.

[28] 楊曼麗, 周明月, 胡雪情, 陳風, 何聰芬, 賈焱. 化妝品經皮滲透研究進展——評價方法及促滲技術. 2020. 日用化學工業(已接收).

發明專利

[1] 賈焱,何聰芬,甘瑤,宋麗雅,成志偉,董坤,劉蕾,一種基於皮膚脂質組學製備適用於早晚的仿生護膚組合物的方法,中國,KLPI170925.

[2] 何聰芬,賈焱,崔樂,江彪,宋麗雅,成志偉,董坤,劉蕾,一種基於皮膚脂質組學製備適用於青年男女的仿生護膚組合物的方法,中國,KLPI170924.

[3] 何聰芬,賈焱,江彪,崔樂,樊琳娜,宋麗雅,成志偉,董坤,劉蕾,一種基於皮膚脂質組學製備適用于敏感皮膚的護膚組合物的方法,中國,KLPI170926.

獲獎情況

[1] 2021年獲得北京工商大學優秀碩士論文指導教師

[2] 2018年入選北京市屬高校青年拔尖人才培育計劃。

[2] 2016年獲得北京工商大學教育教學成果二等獎。

[3] 2015年獲得北京工商大學35歲以下理工類個人科研總分排名前十名。[1]

參考資料