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韩生成，男，北京师范大学生命科学学院教授。
人物简历
1992年毕业于南开大学生物系微生物学专业，获学士学位；1997年获得中国农业大学(原北京农业大学)生物化学及分子生物学专业博士学位，期间主要从事玉米花粉肌动蛋白的纯化和结构分析的研究；1997年7月-1999年6月在中国科学院微生物研究所做博士后，从事转基因水稻抗矮缩病毒的研究；1999年7月-2000年12月在美国加州大学圣地亚哥分校生物科学分部作博士后，研究微管结合蛋白-TANGLED1对玉米叶片细胞分裂及叶片发育的调控；2001年1月-2005年6月在美国杜克大学生物系作博士后，从事植物细胞钙信号的研究；2005年7月-2008年6月在美国弗吉尼亚大学生物系作博士后，从事烟草尼古丁代谢的转录调控的研究；2007年9月被聘为北京师范大学教授，担任“985工程”科技创新平台团队研究员。2008年7月回国工作。
研究内容
植物钙信号发生分子机制：重点探索感受不同内外源因素引起胞质钙离子和核内钙离子增加的受体或离子通道并解析其作用机制，揭示植物钙信号转导新通路。
水稻颖果发育转录调控机制：重点探索水稻初级颖果和次级颖果之间表达差异的关键编码基因或非编码基因作用机制及生物学功能，揭示水稻初次级颖果发育差异的分子机制，为提高水稻产量及改善品质提供基因资源。
研究成果
Yang Han, Yinxing Wang, Yuanjun Zhai, Zhaohong Wen, Jin Liu, Chao Xi, Heping Zhao, Yingdian Wang and Shengcheng Han# (2022) OsOSCA1.1 Mediates Hyperosmolality and Salt Stress Sensing in Oryza sativa. Biology, 11(5): 678.
Doudou Wang, Feifei Huang, Pengcheng Yan, Yanli Nie, Lvli Chen, Jin Luo, Heping Zhao, Yingdian Wang and Shengcheng Han# (2022) Cytosolic and nucleosolic calcium-regulated molecular networks in response to long-term treatment with abscisic acid and methyl jasmonate in Arabidopsis thaliana. Genes 13: 524.
Hanmeng Wang, Zhilin Chu, Shu Chang, Shenghua Jia, Lu Pang, Chao Xi, Jin Liu, Heping Zhao, Yingdian Wang#, Shengcheng Han# (2022) Transcriptomic identification of long noncoding RNAs and their hormone-associated nearby coding genes involved in the differential development of caryopses localized on different branches in rice. Journal of Plant Physiology 271: 153663.
Yihao Li, Kun Liu, Ganlu Tong, Chao Xi, Jin Liu, Heping Zhao, Yingdian Wang, Dongtao Ren, Shengcheng Han# (2022) MPK3/MPK6-mediated ERF72 phosphorylation positively regulates resistance to Botrytis cinerea through directly and indirectly activating the transcription of camalexin-biosynthesis enzymes. Journal of Experimental Botany 73(1): 413-428.
Shenghua Jia, Shu Chang, Hanmeng Wang, Zhilin Chu, Chao Xi, Jin Liu, Heping Zhao, Shengcheng Han# & Yingdian Wang# (2021) Transcriptomic analysis reveals the contribution of auxin on the differentially developed caryopses on primary and secondary branches in rice. Journal of Plant Physiology 256: 153310.
Yuanjun Zhai, Zhaohong Wen, Yang Han, Wenqing Zhuo, Fang Wang, Chao Xi, Jin Liu, Ping Gao, Heping Zhao, Yingdian Wang, Youjun Wang#, Shengcheng Han# (2020) Heterogeneous expression of plasma-membrane-localised OsOSCA1.4 complements osmotic sensing based on hyperosmolality and salt stress in Arabidopsis osca1 mutant. Cell Calcium 91: 102261
Shu Chang, Yixing Chen, Shenghua Jia, Yihao Li, Kun Liu, Zhouhua Lin, Hanmeng Wang, Zhilin Chu, Jin Liu, Chao Xi, Heping Zhao, Shengcheng Han# and Yingdian Wang# (2020) Auxin apical dominance governed by the OsAsp1-OsTIF1 complex determines distinctive rice caryopses development on different branches. PLoS Genetics 16(10): e1009157
Jin Luo, Lvli Chen, Feifei Huang, Ping Gao, Heping Zhao, Yingdian Wang, Shengcheng Han# (2020) Intraorganellar calcium imaging in Arabidopsis seedling roots using the GCaMP variants GCaMP6m and R-CEPIA1er. Journal of Plant Physiology 246–247; 153127
Lili Yue, Liuqing Wang, Yangchun Du, Wei Zhang, Kozo Hamada, Yoshifumi Matsumoto, Xi Jin, Yandong Zhou, Katsuhiko Mikoshiba, Donald L. Gill, Shengcheng Han# and Youjun Wang# (2020) Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells. Cells 9, 275; doi:10.3390/cells9020275
Kun Liu, Yihao Li, Xuena Chen, Lijuan Li, Kai Liu, Heping Zhao, Yingdian Wang# and Shengcheng Han# (2018) ERF72 interacts with ARF6 and BZR1 to regulate hypocotyl elongation in Arabidopsis. J Exp Bot. 69 (16): 3933-3947.
Huang F, Luo J, Ning T, Cao W, Jin X, Zhao H, Wang Y and Han S# (2017) Cytosolic and nucleosolic calcium signaling in response to osmotic and salt stresses are independent of each other in roots of Arabidopsis seedlings. Front. Plant Sci. 8:1648. doi: 10.3389/fpls.2017.01648
Li Y., Yuan F., Wen Z., Li Y., Wang F., Zhu T., Zhuo W., Jin X., Wang Y., Zhao H., Pei Z-M and Han S.# (2015) Genome-Wide Survey and Expression Analysis of the OSCA Gene Family in Rice. BMC Plant Biology 15:261 doi:10.1186/s12870-015-0653-8
Nie Y., Huang F., Dong S., Li L., Gao P., Zhao H., Wang Y., and Han S# (2014) Identification of inositol 1,4,5-trisphosphate-binding proteins by heparin-agarose affinity purification and LTQ ORBITRAP MS in Oryza sativa. Proteomics 14: 2335-2338.[1]