田見暉
人物經歷
學習經歷
1987.09-1991.07:北京農業大學畜牧系，獲農學學士學位;
1992.09-1995.06:北京農業大學動物科技學院，獲農學碩士學位;
2000.09-2003.06:中國農業大學動物科技學院，獲農學博士學位。
工作經歷
1991.07-1992.09:貴州省畜牧獸醫研究所，實習研究員;
1995.06-1998.09:西藏農牧學院，畜牧獸醫系(援藏)，講師、副系主任;
1999.01-2001.09:中國農業大學，動物科技學院，講師;
2001.09-2006.12:中國農業大學，動物科技學院，副教授，碩士生導師;
2004.04-2021.03:中國農業大學，動物科技學院，副院長;
2006.12-至今:中國農業大學，動物科技學院，教授，博士生導師。
社會兼職
中國畜牧獸醫學會動物繁殖學分會理事長
畜禽育種國家工程實驗室副主任
農業部動物遺傳育種與繁殖學科群副主任
畜禽良種產業技術創新戰略聯盟秘書長
國家"十二五"農業與農村科技發展規劃專家組成員
國家"家"農村計劃"動物分子與細胞工程育種技術研究"重點項目首席科學家
研究方向
以建立家畜配子胚胎高效利用技術為目標，主要開展以下工作:① 動物配子和胚胎髮育調控機制，重點關注體外受精(IVF)胚胎髮育異常的表觀調節機制，突破家畜體外胚胎生產的關鍵技術瓶頸;② 家畜繁殖調控技術，重點關注母畜發情/排卵控制，以及母畜子宮容受性等繁殖機能的改善。
教學工作
承擔本科生與研究生教學課程等
本科教學課程:動物繁殖學
研究生教學課程:動物生殖生理學、外文科技文獻研讀-B、動物繁殖學Seminar
學術成果
承擔項目
國家自然基金面上項目，31472092，體外胚胎出生性別比例失衡的分子機制研究，2015.01-2018.12
支撐計劃課題，2011BAD19B01，家畜胚胎保存與性控雙犢誘導技術研究，2011.01-2013.12
863課題，2011AA100303，家畜卵母細胞冷凍、胚胎表觀修飾和體細胞克隆技術研究，2011.01-2015.12
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長江學者特聘教授 田見暉 |
863課題，2008AA101004，家畜精子快速低損傷分離技術研究與應用，2008.01-2011.12
863課題，2008AA101003，家畜卵泡高效誘導發育技術研究與應用，2008.01-2011.12
農業部跨越計劃，優質高產奶牛性別控制技術集成，2007.07-2009.07
國家自然基金面上項目，30671507，脂肪組織特異表達線蟲脂肪酸脫氫酶小鼠模型的建立，2007.01-2009.12
支撐計劃課題，2006BAD14B08，畜禽良種資源高效繁殖和生殖健康關鍵技術研究，2006.11-2008.12
發表論文
Tan K, An L, Miao K, Ren L, Hou Z, Tao L, Zhang Z, Wang X, Xia W, Liu J, Wang Z, Xi G, Gao S, Sui L, Zhu DS, Wang S, Wu Z, Bach I, Chen DB, Tian JH*. Impaired imprinted X chromosome inactivation is responsible for the skewed sex ratio following in vitro fertilization. Proc Natl Acad Sci U S A 2016; 113: 3197-3202
Tan K., Wang X., Zhang Z., Miao K., Yu Y., An L., and Tian JH.*, Downregulation of miR-199a-5p Disrupts the Developmental Potential of In Vitro-Fertilized Mouse Blastocysts. Biol Reprod (2016, in press online)
Tan K, Wang Z, Zhang Z, An L, Tian JH*. IVF affects embryonic development in a sex-biased manner in mice. Reproduction 2016; 151:443-53.
Gao S, Zheng C, Chang G, Liu W, Kou X, Tan K, Tao L, Xu K, Wang H, Cai J, Tian JH*, Gao S. Unique features of mutations revealed by sequentially reprogrammed induced pluripotent stem cells. Nat Commun 2015; 6: 6318.
Ren L, Wang Z, An L, Zhang Z, Tan K, Miao K, Tao L, Cheng L, Zhang Z, Yang M, Wu Z, Tian JH*. Dynamic comparisons of high-resolution expression profiles highlighting mitochondria-related genes between in vivo and in vitro fertilized early mouse embryos. Hum Reprod 2015; 30: 2892-2911.
Di KQ, Gao S, Cui LF, Chang G, Wu FJ, Ren LK, An L, Miao K, Tan K, Tao L, Chen H, Wang ZL, Wang SM, Wu ZH, Gao S, Li XY, Tian JH*. Generation of fully pluripotent female murine-induced pluripotent stem cells. Biol Reprod 2015; 92: 123.
Tan K, An L, Wang SM, Wang XD, Zhang ZN, Miao K, Sui LL, He SZ, Nie JZ, Wu ZH, Tian JH*. Actin Disorganization Plays a Vital Role in Impaired Embryonic Development of In Vitro-Produced Mouse Preimplantation Embryos. PLoS One 2015; 10: e130382.1
Sui L, An L, Tan K, Wang Z, Wang S, Miao K, Ren L, Tao L, He S, Yu Y, Nie J, Liu Q, Xing L, Wu Z, Hou Z, Tian JH*. Dynamic proteomic profiles of in vivo- and in vitro-produced mouse postimplantation extraembryonic tissues and placentas. Biol Reprod 2014; 91: 155.
Jia Z, Zhang J, Zeng W, Zhu Y, Xue J, Xuan B, Tian JH*. Effects of administration of estradiol and progesterone on ovarian stimulation response, and in vitro developmental competence of oocytes in CIDR-treated calves. Anim Biotechnol 2014; 25: 179-187.
Chang G, Gao S, Hou X, Xu Z, Liu Y, Kang L, Tao Y, Liu W, Huang B, Kou X, Chen J, An L, Miao K, Di K, Wang Z, Tan K, Cheng T, Cai T, Gao S, Tian JH*. High-throughput sequencing reveals the disruption of methylation of imprinted gene in induced pluripotent stem cells. Cell Res 2014; 24: 293-306.16
Nie J, An L, Miao K, Hou Z, Yu Y, Tan K, Sui L, He S, Liu Q, Lei X, Wu Z, Tian JH*. Comparative analysis of dynamic proteomic profiles between in vivo and in vitro produced mouse embryos during postimplantation period. J Proteome Res 2013; 12: 3843-3856.
Gao S, Wang ZL, Di KQ, Chang G, Tao L, An L, Wu FJ, Xu JQ, Liu YW, Wu ZH, Li XY, Gao S, Tian JH*. Melatonin improves the reprogramming efficiency of murine-induced pluripotent stem cells using a secondary inducible system. J Pineal Res 2013; 55: 31-39. 4
Pang YW, An L, Wang P, Yu Y, Yin QD, Wang XH, Xin-Zhang, Qian-Zhang, Yang ML, Min-Guo, Wu ZH, Tian JH*. Treatment of porcine donor cells and reconstructed embryos with the antioxidant melatonin enhances cloning efficiency. J Pineal Res 2013; 54: 389-397.
Xia C, Xia W, Yang S, An L, Li X, Wu Z, Zhang J, Wang Z, Tian J*. Effect of antioxidant supplementation on function and fertility of sex-sorted boar spermatozoa. Anim Reprod Sci 2012; 136: 108-114. 9
Cheng WM, Wu ZH, Zhang X, Zhu YB, Pang YW, Guo M, Wang D, Tian JH*. Effects of different activation regimens on pronuclear formation and developmental competence of in vitro-matured porcine oocytes after intracytoplasmic sperm injection. Reprod Domest Anim 2012; 47: 609-614.
Xu XL, Ma W, Zhu YB, Wang C, Wang BY, An N, An L, Liu Y, Wu ZH, Tian JH*. The microtubule-associated protein ASPM regulates spindle assembly and meiotic progression in mouse oocytes. PLoS One 2012; 7: e49303. 7
Miao K, Guo M, An L, Xu XL, Wu H, Wang D, Wu ZH, Tian JH*. A new method to efficiently produce transgenic embryos and mice from low-titer lentiviral vectors. Transgenic Res 2011; 20: 357-363. 7
Ma W, An L, Wu Z, Wang X, Guo M, Miao K, Ma W, Tian JH*. Efficient and safe recipient preparation for transplantation of mouse spermatogonial stem cells: pretreating testes with heat shock. Biol Reprod 2011; 85: 670-677.
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田見暉教授 |
An L, Wu ZH, Wu YF, Zhang XL, Liu X, Zhu YB, Cheng WM, Gao HM, Guo M, Tian JH*. Fertility in single-ovulating and superovulated dairy heifers after insemination with low dose sex-sorted sperm. Reprod Domest Anim 2010; 45: e344-e350.
Cheng WM, An L, Wu ZH, Zhu YB, Liu JH, Gao HM, Li XH, Zheng SJ, Chen DB, Tian JH*. Effects of disulfide bond reducing agents on sperm chromatin structural integrity and developmental competence of in vitro matured oocytes after intracytoplasmic sperm injection in pigs. Reproduction 2009; 137: 633-643.
Cheng WM, Sun XL, An L, Zhu SE, Li XH, Li Y, Tian JH*. Effect of different parthenogenetic activation methods on the developmental competence of in vitro matured porcine oocytes. Anim Biotechnol 2007; 18: 131-141.12
Tian JH*, Wu ZH, Liu L, Cai Y, Zeng SM, Zhu SE, Liu GS, Li Y, Wu CX. Effects of oocyte activation and sperm preparation on the development of porcine embryos derived from in vitro-matured oocytes and intracytoplasmic sperm injection. Theriogenology 2006; 66: 439-448.
發明專利
Method for inducing twin calving. US 20140349934A1 (國際發明專利)
C型鈉肽在促進牛卵母細胞體外成熟中的應用 ZL201210348285.9
來曲唑在用於製備成年牛超數排卵藥物中的應用 ZL201110436200.8
來曲唑在製備激素誘導犢牛卵泡發育藥物中的應用 ZL201110434833.5
一種豬用子宮深部低劑量輸精器械及其輸精器的端部探伸構造ZL201220721931.7
一種製備奶牛性別控制精子的方法 ZL201110059938.7
中國荷斯坦奶牛LHCGR基因作為分子標記的應用 ZL201110036351.4
慢病毒感染胚胎的方法 ZL200910237357.0
培養裝置 ZL201020504203.1
一種消化卵母細胞透明帶的方法 ZL200610012029.7
發表著作
動物種業科技創新戰略研究報道，主編，科學出版社，2015。
動物繁殖理論與生物技術，主編，養殖領域研究生教學用書，中國農業出版社，2010。
動物生殖生理學，副主編，全國高等農業院校教學指導委員會推薦研究生教學用書，中國農業出版社，北京，2006。
獲得榮譽
視頻
母豬定時輸精技術進展-田見暉-中國農業大學2020-10-28
參考來源
- ↑ ，中國農業大學博導、教授，動物遺傳育種與繁殖專家 ,一點資訊, 2021-07-24
- ↑ 林萬龍、杜太生、田見暉任中國農業大學副校長 王濤、龔元石不再擔任 ,金融界, 2020-12-24
- ↑ 田見暉 ,搜狗