檢視马大为的原始碼

{{Infobox person  
| 姓名     =   '''马大为'''
| 民族     =   汉族
| 图像     =  
[[File:马大为1.jpg|缩略图|居中|250px|[http://bnpc.sioc.ac.cn/upload/200902/s_20090220112018187.jpg 原图链接]  [http://bnpc.sioc.ac.cn/?c=3&p=3 来自凤凰网]]]
| 出生日期 =  1963年9月 
| 出生地点 =  河南省社旗
| 国籍     =  中国
| 学历     =  博士
| 职业     =  副所长、博导、研究员
| 毕业院校 =  山东大学、中国科学院
 }}
<p style="text-indent:2em;">1984年毕业于[[山东大学]]化学系， 1989年于中国科学院上海有机化学研究所获博士学位， 1990-1994年在美国匹兹堡大学化学系和Mayo Clinic神经化学和神经生物学研究部进行博士后研究。 现任中国科学院上海有机化学研究所研究员，上海有机化学所副所长，复旦大学兼职教授 。</p >

== 研究方向 ==
<p style="text-indent:2em;">具有重要生理活性的复杂天然产物的全合成及结构-活性关系研究；针对特殊靶点如G-蛋白偶连受体，蛋白激酶，蛋白水解酶和细胞凋亡过程的小分子调节剂的发现；有机合成方法学的发展和其在合成生物活性分子中的应用。</p >

== 获奖及荣誉 ==
<p style="text-indent:2em;">上海市科技精英（2009）
国家自然科学二等奖 （2007）；
上海市科学进步一等奖（2005）；
上海市十大杰出青年（2001）；
中国青年科技奖 （1998）；
求是科技基金会杰出青年学者奖（1998）；</p ><ref>[http://www.ircbc.ac.cn/team_view.php?id=89 研究团队  ]中国科学院生物与化学交叉研究中心</ref>

== 代表论文 ==
<p style="text-indent:2em;">1. Qian Cai, Benli Zou, Dawei Ma*, Mild Ullmann-type biaryl ether formation reaction via combination of ortho-substituent and ligand effects, Angew. Chem. Int. Ed. 2006, 45, 1276. 
2. Dawei Ma*, Yongwen Jiang, Fangping, Chen, Li-kun, Gong, Ke Ding, Yong Xu, Renxiao Wang, Aihua Ge, Jin Ren*, Jingya Li, Jia Li and Qizhuang Ye, Selective inhibition of matrix metalloproteinase isozymes and in vivo protection against emphysema by substituted γ-keto carboxylic acids. J. Med. Chem. 2006, 49, 456.
3. Shouyun Yu, Xianhua Pan and Dawei Ma*, Total syntheses of halipeptins A-D, potent anti-inflammatory cyclic depsipeptides, Chem. Eur. J. 2006, 12, 6572. 
4. Qian Cai, Gang He and Dawei Ma*, Mild and Non-racemization conditions for Ullmann-type diaryl ether formation between aryl halides and tyrosine derivatives, J. Org. Chem. 2006, 71, 5268. 
5. Dawei Ma*, Bin Zou, Guorong Cai, Xiaoyi Hu and Jun O. Liu, Total synthesis of cyclodepsipeptide apratoxin A and its analogues and assessment of their biological activity, Chem. Eur. J. 2006, 12, 7615. 
6. Shanghai Yu, Xiaotao Pu, Tiejun Cheng, Renxiao Wang and Dawei Ma*, Total Synthesis of Clavepictines A and B and Pictamine, Org. Lett. 2006, 8, 3179. 
7. Xiaotao Pu and Dawei Ma*, Facile entry to decahydroquinoline alkaloids. 
Total synthesis of lepadins A-E and H, J. Org. Chem. 2006, 71, 6562. 8. Xiaoan Xie, Yu Chen, Dawei Ma, Enantioselective arylation of 2-methylacetoacetates catalyzed by CuI/trans-4-hydroxy-L-proline at low reaction temperature, J. Am. Chem. Soc. 2006, 128, 16050. 
9. Dawei Ma,* Shanghai Yu, Ben Li,Li Chen,Renhai Chen, Kunqian Yu, Linqi Zhang, Zhiwei Chen, Dafang Zhong, Zheng Gong, Renxiao Wang, Hualiang Jiang and Gang Pei, Synthesis and biological evaluation of 1,3,3,4-tetrasubstituted pyrrolidine CCR5 receptor antagonists. Discovery of a potent and orally bioavailable anti-HIV agent. ChemMedChem. 2007, 2, 187-193. 
10. Benli Zou, Qiliang Yuan, Dawei Ma*, 1,2-Disubstituted benzimidazoles by a Cu-catalyzed cascade aryl amination-condensation process, Angew. Chem. Int. Ed. 2007, 46, 2598. 
11. Gang He, Jing Wang, Dawei Ma*, Highly convergent route to cyclopeptide alkaloids. Total synthesis of ziziphine N, Org. Lett. 2007, 9, 1367. 
12. Zhankui Sun, Shouyun Yu, Zuoding Ding and Dawei Ma*, Enantioselective addition of activated terminal alkynes to 1-acylpyridinium salts catalyzed by u-bis(oxazoline) complexes, J. Am. Chem. Soc. 2007, 129, 9300. 
13. Yu Chen, Xiaoan Xie and Dawei Ma*, Facile access to polysubstituted indoles via a cascade Cu-catalyzed arylation-condensation process, J. Org. Chem. 2007, 72, 9329. 
14. Benli Zou, Qiliang Yuan, Dawei Ma*, Cascade coupling/cyclization process to N-substituted 1,3-dihydrobenzimidazol-2-ones, Org. Lett. 2007, 9, 4291. 
15. Shaolin Zhu, Shouyun Yu, Dawei Ma*, Highly efficient catalytic system for enantioselective Michael addition of aldehydes to nitroalkenes in water,Angew. Chem. Int. Ed. 2008, 47, 545. 
16. Yu Chen, Yuji Wang, Zheming Sun, Dawei Ma*, Elaboration of 2- (trifluoromethyl)-indoles via a cascade coupling-condensation-deacylation process, Org. Lett. 2008, 10, 625. 
17. Weiqing Xie, Derong Ding, Weiwei Zi, Guangyu Li, Dawei Ma, Total synthesis and Structure of Papuamide B, a potent anti-HIV marine cyclodepsipeptide, Angew. Chem. Int. Ed. 2008, 47, 2844. 
18. Li Tan, Dawei Ma, Total synthesis of salinamide A, a potent anti-inflammatory bicyclic depsipeptide, Angew. Chem. Int. Ed. 2008, 47, 3614. 
19. Dawei Ma, Cai Qian, Copper/amino acid catalyzed cross-couplings of aryl and vinyl halides with nucleophiles, Acc. Chem. Res. 2008, 41, 1450. 
20. Jing Wang, Anqi Ma, Dawei Ma, Organocatalytic Michael addition of aldehydes to γ-keto-α,β-unsaturated esters. An efficient entry to versatile chiral building blocks. Org. Lett. 2008, 10, 5425.</p >

== 参考文献==
[[Category:教授]]  [[Category:中国人]]