陳涓涓

陳涓涓 福州大學化學學院

陳涓涓，女，福州大學化學學院副教授。

目錄

人物簡歷

2003.09-2008.07 北京大學 醫學部 本科

2008.09-2013.07 北京大學 化學與分子工程學院 碩博連讀

2014.08-至今 福州大學 工作

研究方向

腫瘤治療和分子診斷

科研項目

1. 福建省自然科學基金項目

2.福建省教育廳科技項目

3.福州大學引進人員基金

學術成果

論文

• 1. Erlotinib Analogue-substituted Zinc(II) Phthalocyanines for Small Molecular Target-based Photodynamic Cancer Therapy，Chinese Journal of Chemistry，2016.10.01，34（10）：983~988.
• 2. A sensitive and quantitative autolysosome probe for detecting autophagic activity in live and prestained fixed cells., Autophagy, 2013, 9(6): 894-904.
• 3. Rational design of ZnSalen as a single and two photon activatable fluorophore in living cells, Chemical Science, 2012, 3(11):3315-3320.
• 4. [small beta]-Lactonization of fluorinated porphyrin enhances LDL binding affinity, cellular uptake with selective intracellular localization, Chemical Science, 2014, 5(2): 558-566.
• 5. Luminescent zinc salen complexes as single and two-photon fluorescence subcellular imaging probes，Chemical Communications, 2011, 47(8): 2435-2437.
• 6. A unique series of reversibly switchable fluorescent proteins with beneficial properties for various applications, Proceedings of the National Academy of Sciences of the United States of America, 2012, 109(12): 4455-4460.
• 7. β-Ionic Conjugated Chlorin-Type Photosensitizers Based on Porpholactone: Synthesis, Photophysical Properties, and Photodynamic Activity，ChemPlusChem, 2015, 80(1): 237-252.
• 8. Construction of an orthogonal ZnSalen/Salophen library as a colour palette for one- and two-photon live cell imaging, Chemical Science, 2014, 5(6): 2318-2327.
• 9. Rational design of true monomeric and bright photoactivatable fluorescent proteins，Nature Methods, 2012, 9 (7): 727-729.
• 10. Light-induced protein translocation by genetically encoded unnatural amino acid in Caenorhabditis elegans，Protein & Cell, 2013, 4(12): 883-886.