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周源(研究員)

周源
北京大學基礎醫學院

周源,男,北京大學基礎醫學院研究員。

目錄

人物簡介

2010年本科畢業於首都師範大學生物科學專業,2015年於中國農業大學生物信息學專業獲理學博士學位,後於北京大學醫學部從事博士後研究。現就職於北京大學基礎醫學院醫學信息學系,從事生物信息學研究,目前主要研究興趣為轉錄組學(含非編碼RNA)與表觀轉錄組學數據的計算分析。先後開發了CCPPI、SRAMP等10餘個生物信息學工具,總使用量超過4萬人次。以(含共同)第一或通訊作者在Nucleic Acids Research, Briefings in Bioinformatics等專業期刊上發表SCI論文22篇,其它署名SCI論文15篇。

研究方向

1. 疾病相關轉錄組數據的計算分析;

2. RNA修飾表觀轉錄組學的生物信息學研究。

學術成果

論文

1、Zhan Tong, Qinghua Cui, Juan Wang*, Yuan Zhou*. TransmiR v2.0: an updated transcription factor-microRNA regulation database. Nucl Acids Res,2018, in press, doi: 10.1093/nar/gky1023.

2、Jianwei Li*, Xiaofen Han, Yanping Wan, Shan Zhang, Yingshu Zhao, Rui Fan, Qinghua Cui, Yuan Zhou*. TAM 2.0: tool for microRNA set analysis. Nucl Acids Res, 2018, 2018,46(W1):W180-W185.

3、Chunmei Cui#, Weili Yang#, Jiangcheng Shi, Yong Zhou, Jichun Yang, Qinghua Cui*, Yuan Zhou*. Identification and analysis of human sex-biased microRNAs. Genomics, Proteomics Bioinformatics, 2018, 16(3): 200-211.

4、Yuan Zhou*, Qinghua Cui*. Comparative Analysis of Human Genes Frequently and Occasionally Regulated by m6A Modification. Genomics, Proteomics Bioinformatics, 2018, 16(2):127-135.

5、Wenjing Xu#, Yuan Zhou#, Guoheng Xu*, Bin Geng*, Qinghua Cui*. Transcriptome analysis reveals non-identical microRNA profiles between arterial and venous plasma. Oncotarget, 2017, 8(17):28471-28480.

6、Hong Li, Yuan Zhou*, Ziding Zhang*. Network Analysis Reveals a Common Host-Pathogen Interaction Pattern in Arabidopsis Immune Responses. Front Plant Sci, 2017, 8:893.

7、Shiping Yang, Hong Li, Fei He, Yuan Zhou*, Ziding Zhang*. Critical assessment and performance improvement of plant-pathogen protein-protein interaction prediction methods. Brief Bioinform, 2017, in press, doi: 10.1093/bib/bbx123.

8、Yuan Zhou*, Pan Zeng, Yan-Hui Li, Ziding Zhang, Qinghua Cui*. SRAMP: prediction of mammalian N6-methyladenosine (m6A) sites based on sequence-derived features. Nucl Acids Res, 2016,44(10):e91.

9、Yuan Zhou#, Ying-Si Zhou#, Fei He, Jiangning Song*, Ziding Zhang*. Can simple codon pair usage predict protein-protein interaction? Mol Biosyst, 2012, 8(5): 1396-1404.

10、Fei He#, Yuan Zhou#, Ziding Zhang*. Deciphering the Arabidopsis floral transition process by integrating a protein-protein interaction network and gene expression data. Plant Physiol, 2010, 153(4): 1492-1505.[1]

參考資料